Chile forward Alexis Sanchez has been ruled out of the Copa America group stage because of a foot problem, the Chilean FA said on Saturday.
The 32-year-old Internazionale forward injured a plantar muscle while training with the national team on Friday and will need at least two weeks to recover, the entity said in a statement.
It added that Sanchez would undergo treatment in Chile under the supervision of the national team's medical staff.
Chile will begin their Copa America campaign against Argentina at Rio de Janeiro's Olympic Stadium on Monday.
Martin Lasarte's team will also meet Uruguay, Bolivia and Paraguay in the group stage.
The Copa America was moved to Brazil last month, having originally been slated for Argentina and Colombia.
Colombia was stripped of its host status due to civil unrest while Argentina was dropped because of rising coronavirus cases.